Blar i forfatter "Pettersen, Veronika K."

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    • Development of early life gut resistome and mobilome across gestational ages and microbiota-modifying treatments 

      Bargheet, Ahmed; Klingenberg, Claus Andreas; Esaiassen, Eirin; Hjerde, Erik; Cavanagh, Jorunn Pauline; Bengtsson-Palme, Johan; Pettersen, Veronika K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-13)
      Background - Gestational age (GA) and associated level of gastrointestinal tract maturation are major factors driving the initial gut microbiota composition in preterm infants. Besides, compared to term infants, premature infants often receive antibiotics to treat infections and probiotics to restore optimal gut microbiota. How GA, antibiotics, and probiotics modulate the microbiota’s core ...

    • Inferring early-life host and microbiome functions by mass spectrometry-based metaproteomics and metabolomics 

      Pettersen, Veronika K.; Antunes, Luis Caetano Martha; Dufour, A; Arrieta, Marie-Claire (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-20)
      Humans have a long-standing coexistence with microorganisms. In particular, the microbial community that populates the human gastrointestinal tract has emerged as a critical player in governing human health and disease. DNA and RNA sequencing techniques that map taxonomical composition and genomic potential of the gut community have become invaluable for microbiome research. However, deriving a ...

    • Metaproteomic profiling of fungal gut colonization in gnotobiotic mice 

      Pettersen, Veronika K.; Dufour, Antoine; Arrieta, Marie-Claire (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-22)
      <b><p>Background</b> Eukaryotic microbes can modulate mammalian host health and disease states, yet the molecular contribution of gut fungi remains nascent. We previously showed that mice exclusively colonised with fungi displayed increased sensitivity to allergic airway inflammation and had fecal metabolite profiles similar to germ-free mice. This marginal effect on the host metabolome suggested ...

    • Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants 

      Samara, Jumana; Moossavi, Shirin; Alshaikh, Belal; Ortega, Van A.; Pettersen, Veronika K.; Ferdous, Tahsin; Hoops, Suzie L.; Soraisham, Amuchou; Vayalumkal, Joseph; Dersch-Mills, Deonne; Gerber, Jeffrey S.; Mukhopadhyay, Sagori; Puopolo, Karen; Tompkins, Thomas A.; Knights, Dan; Walter, Jens; Amin, Harish; Arrieta, Marie-Claire (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-11)
      Probiotics are increasingly administered to premature infants to prevent necrotizing enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and immunity are poorly understood. Using a randomized intervention trial in extremely premature infants, we tested the effects of a probiotic product containing four strains of Bifidobacterium species autochthonous to the infant ...